We have commissioned
four scientists, who together have well over 147 Patents in inhalation related
work, to develop heat-generated aerosol inhalers. These four scientists have
137 years experience in developing inhalation devices and aerosolizing compounds.
DOES, Inc. has been
developing inhalers for pulmonary ingestion of drugs since 1985.
We
are looking for a partner to continue development of
a 'new unique inhaler' that no one else has.
a) the new unique device produces Heat
Generated Drug Delivery Aerosols (HGDDA) that aerosolizes
pharmaceuticals for inhalation with the following advantages:
1) does not
cause degradation (decomposition) of the drug
2)
will deliver your required particle
size, MMAD .2 to 3 microns or smaller
3)
solves the agglomeration problem
4) delivers a precise drug dosage
5) has thermostatically controlled temperature
6)
expected
to deliver 60-90% of the drug
7) delivers
little or no pyrolysis degradation compounds
b) We have developed
the important materials to effectively deliver an aerosol generated by the
aerosolization device described above.
c) We have experience
with many drug carriers to insure effective drug delivery.
d) Working with your
people, we can configure this device to deliver each drug quantity; using the
proper temperature, with the required particle size delivered.
e) Our product pipeline includes:
1)
a miniaturized drug vaporization device
(HGDDA) approximately 1" by 4" in size
that
uses heat to generate
an aerosol that can be inhaled - with the above
advantages numbered 1), 2), 3), 4), 5),6, and 7).
2)
an active
DPI device that will deliver combination drugs.
3)
an add on device that
will increase the efficiency of current inhaler devices. This add on device can
be used
for many inhaled drugs.
4)
A passive
DPI device that will deliver combination drugs.
We would like to work with a partner to
develop inhalers for several purposes of importance:
1) Over 200 drugs that can be
aerosolized using heat
2) Inhaled powdered
drugs, e.g. insulin
4) Drugs needing
quick efficacy
DOES is known by
select prestigious clients in:
a) Drug Delivery
Devices
b) Inhalation of
aerosols
c) Dry Powder Metal
Alloy Development for General Electric
d) Lockheed Martin F-16 Fighter Plane
(worlds most popular)
e) Military air
defense systems, including Patriot missiles used in the Gulf war
f) Certification and
patenting of copper alloy
g) National
Aeronautics and Space Administration (NASA) (Patented)
h) M&M/MARS, Inc. - helped develop many
products including M&Ms and my favorite Snickers,
#1 candy bar in the world
i) Development of
many other consumer products
DOES has sponsored seminars in
London,
San Francisco,
Honduras,
Nicaragua, and
Winston-Salem on “How to Develop Products.” A famous
British developer, Dr. George E.P. Box, FRS was a featured speaker at these
seminars. By clicking on references on this web site, please see my personal
reference letter by Dr. George E.P. Box, FRS, Fellow
in the Royal Society.
Our research has
shown that inhaled pharmaceuticals have the following advantages:
1) Smaller amounts of
the drug are more effectively delivered
2) Any patient can
use an aerosol regardless of their coordination status
3) A drug delivered
by inhalation better targets areas of need
4) Systemically
delivered drugs can have side effects, whereas locally
delivered drugs
reduce that risk
5) The particle size
and agglomeration problems can be solved
6) Inhaled
pharmaceuticals can act quicker
William B. Line,
President
DOES,
Inc.
2531 Woodbine Road
Winston-Salem,
NC
27104
Direct Tele: (336) 624-2294
Email –
Bill@doesinc.com